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Clobevate Cream 20G Uses, Price, Side Effect, and More

Clobevate cream is a topical steroid that contains “Clobetasol Propionate BP 0.05% w/w.” It is a powerful corticosteroid used to treat various skin conditions such as eczema, psoriasis, dermatitis, and allergic reactions. It works by reducing inflammation, itching, and redness in the affected skin areas.

Marketed By: GlaxoSmithKline (GSK)

Drug Class: Corticosteroid

Generic: Clobetasol Propionate

Clobevate Cream Mechanism of Action

Clobetasol Propionate is a potent corticosteroid that works by reducing inflammation and immune system responses in the body. After applying it to the affected area of the skin, it stops the activity of chemicals and cells that cause inflammation, redness, and itching.

Clobevate Cream Uses

Clobevate cream uses include

  • Psoriasis
  • Eczema
  • Contact Dermatitis
  • Lichen Planus
  • Discoid Lupus Erythematosus (DLE)
  • Seborrheic Dermatitis

Psoriasis

Clobevate cream can be used to treat psoriasis, a chronic skin condition characterized by the buildup of skin cells that form scales and red patches. The cream works by reducing inflammation and suppressing the immune response, which helps to slow down the growth of skin cells and alleviate symptoms.

Eczema

Clobevate cream is also used in the treatment of eczema, a condition where red patches form on the skin, accompanied by allergies and swelling. The cream helps to eliminate bacteria and is particularly useful for atopic dermatitis and chronic eczema.

Contact Dermatitis

This is a skin condition caused by an allergic or harmful chemical reaction. For example, the use of soap, detergent, or perfume can cause itching or redness on the skin. Clobevate cream controls this allergic response and helps restore normal skin condition.

Lichen Planus

This is a condition in which inflammation or itchy spots develop on the skin and mucous membranes (such as in the mouth or genital areas). Clobevate cream reduces inflammation, smooths the skin surface, and alleviates the effects of the disease.

Discoid Lupus Erythematosus (DLE)

This is an autoimmune disease that causes sores and spots on the skin, especially on areas exposed to the sun. Clobevate cream reduces inflammation of these sores and helps improve the skin condition.

Seborrheic Dermatitis

This is a skin disorder that primarily affects the scalp and face, causing redness and oily patches on the skin. Clobevate cream reduces this inflammation and redness, improving the skin condition.

Clobevate Cream Dosage

Clobevate cream is applied as a thin layer to the affected area. It is effective to apply the cream 1 to 2 times a day.

It should only be used for up to 2 weeks. If longer use is necessary, it should be done only under the advice of a doctor.

This cream is used for short-term application, and long-term (chronic) use should be avoided.

Clobevate Cream Missed Dosage

If you miss an application of Clobevate cream, apply it as soon as you remember. However, if the next dose is near, skip the missed dose and return to your regular schedule. Never apply the cream twice to make up for a missed dose, as this could damage the skin.

Clobevate Cream Overdose

If an excessive amount of cream is used or applied for a prolonged period without guidance, it can cause thinning of the skin, stretch marks, burning, and changes in skin color. In case of overdose, immediately wash the affected area and consult your doctor. Always use this medication with caution and only as directed by your doctor.

How to Apply Clobevate Cream?

  1. Wash and dry the affected skin area thoroughly before applying the cream.
  2. Take a small amount of cream on your fingers and apply a thin layer to the affected area.
  3. Gently rub the cream so that it is completely absorbed into the skin.
  4. Do not cover the treated area with a bandage or dressing.
    Wash your hands after applying the cream (unless your hands are the treated area).
  5. Apply the cream at the same time every day to maintain a consistent effect of the medication.
  6. Do not apply more than the prescribed amount of cream, and do not use it for longer than the recommended duration; only follow the instructions of a skin specialist.

Clobevate Cream Precautions

  • Do not apply Clobevate cream on open wounds, ulcers, or broken skin.
  • This cream may cause further irritation or damage to these areas.
  • Keep the cream away from the eyes, inside the nose, or the mouth.
  • If it accidentally gets into the eyes, rinse immediately with clean water and consult a doctor if necessary.
  • Avoid using Clobevate cream for long periods, especially on the face.
  • Prolonged use can thin the skin and increase the risk of infection.
  • Children’s skin is more sensitive, so use this cream only as directed by a doctor.
  • Prolonged use or large quantities in children can affect their hormonal system.

Is Clobevate Cream Safe in Pregnancy and Breastfeeding?

Clobevate cream should be used with caution during pregnancy as it falls under Pregnancy Category C, meaning animal studies have shown negative effects on fetal development from its active ingredients, but complete research on pregnant women is lacking.

This medication may be passed into breast milk and could harm a nursing infant. Therefore, pregnant or breastfeeding women should consult their doctor or gynecologist before using this cream.

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Clobevate Cream Contraindications

  • Do not use Clobevate cream if the patient is allergic to any type of corticosteroid.
  • Allergic reactions may include burning, redness, itching, or rashes on the skin.
  • Always inform your doctor about your allergies before starting the medication.

Clobevate Cream Alternative

  • Dermovate Cream (Clobetasol Propionate 0.05%)
  • Halovate Cream (Halobetasol Propionate 0.05%)
  • Betnovate Cream (Betamethasone Valerate 0.1%)
  • Elocon Cream (Mometasone Furoate 0.1%)
  • Fluocinonide Cream (0.05%)

Clobevate Cream Side Effects

Clobevate cream, if not used properly, may cause some side effects.

  • Skin Thinning – Atrophy
  • Stretch Marks
  • Redness or Irritation
  • Hair Growth – Hypertrichosis
  • Skin Discoloration
  • Allergic Reactions

Skin Thinning – Atrophy

Prolonged use of Clobevate cream can thin the skin, which may become more prone to tearing or injury. This side effect is especially common on the face when used long-term.

Stretch Marks

Excessive use of the cream can cause stretch marks (striae) on the skin, typically in areas where the skin is stretched or tight.

Redness or Irritation

After applying the cream, the skin may experience redness, irritation, or itching. This irritation usually occurs during the initial use but may increase if the cream is not discontinued.

Hair Growth – Hypertrichosis

Some people may experience unexpected hair growth (hypertrichosis) on their face or body with the use of Clobevate cream. This hair growth typically appears in areas where the cream has been applied.

Skin Discoloration

The cream may alter the color of the skin. This discoloration is more commonly seen in individuals who use the cream for extended periods.

Allergic Reactions

If someone is allergic to corticosteroids, they may experience an allergic reaction to Clobevate cream.

Clobevate Cream Rare Side Effects

  • Hormonal Imbalance
  • Glaucoma
  • Adrenal Suppression

Hormonal Imbalance

If Clobevate cream is used in excessive amounts or for long periods, it can affect the body’s hormonal system.

Glaucoma

If Clobevate cream is applied near the eyes, it can cause glaucoma, which is an increase in eye pressure that may damage the optic nerve.

Adrenal Suppression

Long-term and excessive use of the cream can lead to adrenal suppression, where the adrenal glands do not function properly, and cortisol (the stress hormone) levels in the body decrease.

Clobevate Cream Price

Talking about the price of Clobevate cream, we have seen three price increases in the past two months. Initially, Clobevate cream was priced at Rs 112, then it went up to Rs 143, and now its current price is Rs162. If the price of this cream increases again in the future, I will make every effort to update it here.

Clobevate Cream Storage Instructions

  • It is important to store Clobevate cream properly to ensure its effectiveness.
  • Store the cream at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep the cream away from moisture (water).

No, Clobevate cream should not be used on the face unless specifically prescribed by a doctor. The skin on the face is thinner and more sensitive, making it more prone to side effects like thinning of the skin, redness, and increased risk of infection. Prolonged use on the face can also lead to conditions like perioral dermatitis (rash around the mouth) or skin discoloration. Always consult a dermatologist before using Clobevate cream on your face.

Clobevate cream is not specifically designed for use on the scalp or hair. However, if prescribed by a doctor for a scalp condition like seborrheic dermatitis or psoriasis, it can be applied carefully to the affected scalp areas. To use it on the scalp, part the hair to expose the skin and apply a thin layer of the cream directly to the affected area, avoiding excessive application. Always follow your doctor’s instructions and avoid using the cream as a general hair product.

Talking about the price of Clobevate cream, we have seen three price increases in the past two months. Initially, Clobevate cream was priced at Rs 112, then it went up to Rs 143, and now its current price is Rs162. If the price of this cream increases again in the future, I will make every effort to update it here.

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